Blood collection tube holders are essential for safe and sterile blood sampling, requiring biocompatibility, sterility, and leak-proof seals. These holders are made of medical-grade plastics like PP and PC, demanding a clean, particle-free assembly process. Traditional adhesive bonding may introduce chemical contaminants, while ultrasonic welding generates particles that can contaminate blood samples. DaokeDao plastic laser welding produces no debris or contaminants, ensuring the sterility of blood collection tube holders. The non-contact process forms a molecular bond that meets USP Class VI and ISO 10993 biocompatibility standards, preventing chemical leaching into blood samples. It achieves leak-proof seals (leakage rate ≤0.005ml/min), ensuring no blood leakage during sampling. Our systems are cleanroom-compatible (ISO 7), supporting high-volume production (up to 180 units/hour) with consistent quality. By ensuring sterility and biocompatibility, DaokeDao laser welding helps medical device manufacturers improve sampling safety and comply with regulatory requirements (FDA 21 CFR Part 820).